HEART VALVE DAMAGE & PPH
EXPLAINED
The two most common heart valve
disorders associated with the use of fenfluramine (pondimin) and
dexfenfluramine (Redux) are aortic valve regurgitation and mitral valve
regurgitation. Aortic valve regurgitation and mitral regurgitation occur when
the aortic and mitral valves are damaged or not working properly. Heart valves
help blood flow in only one direction as it moves between different chambers
of the heart and into and out of the heart. Aortic valve regurgitation occurs
when the flaps of the aortic heart valve do not form a tight seal, which
allows blood to leak backwards through the valve when the heart muscle
relaxes. Aortic valve regurgitation may reduce blood flow to organs throughout
the body, including the heart muscle itself. As a result of the reduced blood
flow, the heart may need to pump harder, which over years, may enlarge the
lower left heart chamber.
During the early stages of
aortic valve regurgitation, a person may not experience any symptoms, but the
reduced blood flow eventually can cause chest pain, palpitations or irregular
heartbeats (arrhythmias), a serious infection in the heart (endocarditis), heart
failure, and in rare cases, sudden death. Sometimes a person may only notice
symptoms once heart failure develops. There are certain instances when aortic
valve regurgitation can occur suddenly, and will include severe symptoms such as
shortness of breath and extreme fatigue, which may need immediate medical
attention. Also, if the patient's symptoms include severe shortness of breath
and swelling in one's ankles or feet, this may be a fatal condition known as
primary pulmonary hypertension or PPH . Medications to lower blood pressure are
usually used to treat aortic valve regurgitation. If the valve leakage is severe
and the heart is unable to keep up with the increase in pumping, surgery may be
needed to replace the aortic valve. Like aortic valve regurgitation, mitral
regurgitation usually develops over many years. In the case of mitral valve
regurgitation, a significant amount of blood flows back into the left atrium
through the leaky mitral valve. In an attempt to circulate this extra blood, the
left ventricle pumps harder and may enlarge over time. After many years of
increase pumping, the left ventricle may become weaker and symptoms of heart
failure can develop. Mitral valve regurgitation,is a common disorder, but the
disorder can range from mild to severe cases.
Some people
will never develop symptoms and the condition may not get worse, but mitral
valve regurgitation can also develop suddenly. A person may experience symptoms
such as severe shortness of breath (dyspnea), fluid in the lungs and chest pain.
People who develop sudden mitral regurgitation almost always need urgent surgery
to repair or replace their mitral valve. A number of causes can lead to both
aortic valve regurgitation and mitral regurgitation. Some causes include
conditions such as aortic valve stenosis and endocarditis; infections such as
rheumatic fever and syphilis; injury, such as trauma to the heart valve or
aorta; inherited and autoimmune diseases; and heart abnormalities present from
birth. Studies have shown that the previous use of certain weight-loss
medications fenfluramine (pondimin) and dexfenfluramine (Redux), appear to
greatly increase the risk of heart valve disease. (pondimin) and dexfenfluramine
(Redux), appear to greatly increase the risk of heart valve disease.
LEGAL OPTIONS FOR PPH PATIENTS
If
you or a loved one have been diagnosed with Primary Pulmonary Hypertension (PPH),
then you may have a right to file a individual legal action against the
manufacturers of the diet pills or others. Due to the nature of this serious and
devastating disease process, PPH patients are urged to contact an attorney
immediately after he or she has been informed of their Primary Pulmonary
Hypertension diagnosis. Many
important legal issues need to be addressed early after a PPH diagnosis, that
can affect the outcome of the PPH litigation. Call us for a Free Confidential
Consultation. Talk with a Board Certified Personal Injury Trial Lawyer about
your legal rights of a PPH claim against the diet drug industry and others. No
Fees or Expenses Charged unless we make a Recovery for You.
Call Us Toll Free at 1-800-883-9858
or 1-800-468-4878 or E-mail
us your questions on Free
Case Evaluation Form.
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